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Date : 2008-02-19
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DrugLike Properties Concepts Structure Design and ~ DrugLike Properties Concepts Structure Design and Methods from ADME to Toxicity Optimization Second Edition provides scientists and students the background and tools to understand discover and develop optimal clinical candidates This valuable resource explores physiochemical properties including solubility and permeability before exploring how compounds are absorbed distributed and metabolized safely and stably
Druglike Properties Concepts Structure Design and Methods ~ Individual druglike properties are discussed from a practical point of view such as solubility permeability and metabolic stability with regard to fundamental understanding applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance
Druglike Properties Concepts Structure Design and ~ Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target typically only a fraction of these have sufficient ADMETox properties to become a drug product
DrugLike Properties ScienceDirect ~ DrugLike Properties Concepts Structure Design and Methods from ADME to Toxicity Optimization Second Edition provides scientists and students the background and tools to understand discover and develop optimal clinical candidates This valuable resource explores physiochemical properties including solubility and permeability before exploring how compounds are absorbed distributed and metabolized safely and stably
Druglike Properties Concepts Structure Design and ~ Understanding ADMETox is critical for all drug researchers owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery If the properties are weak the candidate will have a high risk of failure or be less desirable as a drug product
DrugLike Properties Concept Structure Design and ~ DrugLike Properties Concepts Structure Design and Methods from ADME to Toxicity Optimization Second Edition provides scientists and students the background and tools to understand discover
DrugLike Properties 2nd Edition ~ DrugLike Properties Concepts Structure Design and Methods from ADME to Toxicity Optimization Second Edition provides scientists and students the background and tools to understand discover and develop optimal clinical candidates This valuable resource explores physiochemical properties including solubility and permeability before exploring how compounds are absorbed distributed and metabolized safely and stably
Druglike Properties Concepts Semantic Scholar ~ Druglike Properties Concepts Structure Design and Methods Academic Press is an imprint of Elsevier 30 Corporate Drive Suite 400 Burlington MA 01803 USA 525 B Street Suite 1900 San Diego California 921014495 USA 84 Theobald’s Road London WC1X 8RR UK This book is printed on acidfree paper
DrugLike Properties Concepts Structure Design and ~ Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target typically only a fraction of these have sufficient ADMETox properties to
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